产品货号：
Z10727
中文名称：
Alpha E-Catenin/CTNNA1抗体
英文名称：
Anti-Alpha E-Catenin/CTNNA1 Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Alpha E-Catenin/CTNNA1 Antibody |
| 指标别名 | alpha catenin;Alpha E catenin;Alpha E-Catenin;Cadherin associated protein;CAP102;Catenin alpha 1;CTNNA1;α-catenin;α-E-catenin;αE-catenin |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | FCM |
| 基因名称 | CTNNA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CTNNA1 recombinant protein (Position:D143-D292).Human CTNNA1 shares 98% amino acid (aa) sequence identity with mouse CTNNA1. |
| 偶联物 | DyLight 488 |
| 激发/发射光谱 | Amax=488nm;Emax=515～545nm |
| 成分 | Each vial contains 50% glycerol,0.9% NaCl,0.2% Na2HPO4,0.02% NaN3. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | At -20˚C for one year from date of receipt.Avoid repeated freezing and thawing.Protect from light. |
| 背景资料 | CTNNA1,also known as Catenin alpha-1 or Catenin (cadherin-associated protein),alpha 1,is a protein that in humans is encoded by the CTNNA1 gene.It is mapped to 5q31.2.When surface epithelium CTNNA1 was ablated,hair follicle development was blocked and epidermal morphogenesis was dramatically affected,with defects in adherens junction formation,intercellular adhesion,and epithelial polarity.In vitro,CTNNA1 null keratinocytes were poorly contact inhibited and grew rapidly.These differences were not dependent upon intercellular adhesion and were in marked contrast to keratinocytes conditionally null for another essential intercellular adhesion protein,desmoplakin Knockout keratinocytes exhibited sustained activation of the Ras-MAPK cascade due to aberrations in growth factor responses.It is concluded that features of precancerous lesions often attributed to defects in cell cycle regulatory genes can be generated by compromising the function of CTNNA1. |
| Uniprot ID | P35221 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：Alpha E-Catenin/CTNNA1抗体，Alpha E-Catenin抗体，CTNNA1多抗，Anti-Alpha E-Catenin/CTNNA1 Antibody